Development and validation of a High performance liquid chromatography- Mass spectrometry method for 17a-methyltestosterone in Aquatic water systems

Development and Application of a Validated Liquid Chromatography-Mass Spectrometry Method for the Determination of Dexchlorpheniramine Maleate in Human Plasma

     A convenient liquid chromatographic-single Quadrupole mass spectrometric (LC-MS) method was developed and validated for dexchlorpheniramine maleate (INN name: chlorphenamine) determination in human plasma. The need for just a single liquid-liquid extraction with ethyl acetate and being highly sensitive were the advantages of this method. The linearity was also excellent over the range of 1...

Development and Validation of Bioanalytical Method for Simultaneous Estimation of Nebivolol Enantiomers in Human Plasma Using Liquid Chromatography-tandem Mass Spectrometry

The present study describes a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the simultaneous determination of S-RRR and R-SSS nebivolol (nebivolol enantiomers) in human plasma using solid phase extraction technique. Method of both S-RRR and R-SSS nebivolol (nebivolol enantiomers) has been developed and validated using racemic nebivolol D4 as an internal standard. Analytes...

development and validation of high performance liquid chromatography for determination of nystatin in pharmaceutical formulations

A quick and easy high performance liquid chromatography method for evaluation of cefixime in human plasma

Cefixime is essential member of orally energetic third generation cephalosporin and has tremendous activity aligned with many pathogens. The virtual bioavailability of a newly industrial dispersible tablet as compared with a recognized identified formulation.  A simple and available reversed-phase HPLC method with UV detection has been urbanized and validate for cefixime evaluate in human p...

Validation of the analysis method of 25 pesticide residues in rice using LC-MS/MS device (liquid chromatography-mass spectrometry)

Introduction: In recent years, due to the increase in the use of pesticides in agricultural products and its entry into the human food chain, there has been an increase in concerns about the health of food among people. Therefore, the purpose of conducting this research is to validate the analysis method. 25 pesticide residues in rice using LC-MS/MS. Methods: In this research, a simultaneous an...